Colchicinoids from Colchicum Crocifolium Boiss. (Colchicaceae)
- UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
- Nicholas Oberlies, Patricia A. Sullivan Distinguished Professor of Chemistry (Creator)
- Institution
- The University of North Carolina at Greensboro (UNCG )
- Web Site: http://library.uncg.edu/
Abstract: A new colchicinoid from Colchicum crocifolium Boiss. (Colchicaceae) was isolated and identified as N,N-dimethyl-N-deacetyl-(-)-cornigerine (5), along with four known compounds, but new to the species: (-)-colchicine (1), (-)-demecolcine (2), (-)-N-methyl-(-)-demecolcine (3) and 3-demethyl-N-methyl-(-)-demecolcine (4). All isolated compounds showed potent cytotoxicity against a human cancer cell panel.
Colchicinoids from Colchicum Crocifolium Boiss. (Colchicaceae)
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Created on 1/31/2019
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Additional Information
- Publication
- Natural Product Research, 24:2, 152-159. PMID:20077308; DOI: 10.1080/14786410902941097
- Language: English
- Date: 2010
- Keywords
- Colchicum crocifolium, colchicinoids, Jordan medicinal plants, colchicine