Feasibility of image-guided radiotherapy based on helical tomotherapy to reduce contralateral parotid dose in head and neck cancer

ECU Author/Contributor (non-ECU co-authors, if there are any, appear on document)

Dave Abraham (Creator)

Misty Ceizyk (Creator)

Alexander Chi (Creator)

Anand Desai (Creator)

Russ Hamilton (Creator)

Siyoung Jang (Creator)

Ulf Karlsson (Creator)

Shane P Krafft (Creator)

Nam P Nguyen (Creator)

Benjamin Slane (Creator)

Lexie Smith-Raymond (Creator)

Michelle Stevie (Creator)

Vincent Vinh-Hung (Creator)

Paul Vos (Creator)

Institution

East Carolina University (ECU )

Web Site: http://www.ecu.edu/lib/

Abstract: Background To evaluate the feasibility of image-guided radiotherapy based on helical Tomotherapy to spare the contralateral parotid gland in head and neck cancer patients with unilateral or no neck node metastases. Methods A retrospective review of 52 patients undergoing radiotherapy for head and neck cancers with image guidance based on daily megavoltage CT imaging with helical tomotherapy was performed. Results Mean contralateral parotid dose and the volume of the contralateral parotid receiving 40?Gy or more were compared between radiotherapy plans with significant constraint (SC) of less than 20?Gy on parotid dose (23 patients) and the conventional constraint (CC) of 26?Gy (29 patients). All patients had PTV coverage of at least 95% to the contralateral elective neck nodes. Mean contralateral parotid dose was, respectively, 14.1?Gy and 24.7?Gy for the SC and CC plans (p?

Additional Information

Publication

Other

BMC Cancer; 12: p. 175-175

Language: English

Date: 2012

Keywords

Head and neck cancer, Parotid sparing, Tomotherapy

Email this document to