The Actin Binding Protein Fesselin is a Member of the Synaptopodin Family
- ECU Author/Contributor (non-ECU co-authors, if there are any, appear on document)
- Brent Beall (Creator)
- Joseph M. Chalovich (Creator)
- Hans W. Heid (Creator)
- Mechthild M. Schroeter (Creator)
- Institution
- East Carolina University (ECU )
- Web Site: http://www.ecu.edu/lib/
Abstract: Fesselin is a natively unfolded protein that is abundant in avian smooth muscle. Like many natively nfolded proteins fesselin has multiple binding partners including actin myosin calmodulin and ŽÂ±-actinin. Fesselin accelerates actin polymerization and bundles actin. These and other observations uggest that fesselin is a component of the cytoskeleton. We have now cloned fesselin and have etermined the cDNA derived amino acid sequence. We verified parts of the sequence by Edman nalysis and by mass spectroscopy. Our results confirmed fesselin is homologous to human ynaptopodin 2 and belongs to the synaptopodin family of proteins. Originally published Biochem Biophys Res Commun. Vol. 371 No. 3 July 2008
Additional Information
- Publication
- Other
- Biochemical and Biophysical Research Communications. 371:3(July 2008) p. 582-586.
- Language: English
- Date: 2011
- Keywords
- fesselin, synaptopodin, myopodin, actin binding protein, actin polymerization, Ca-calmodulin regulation
| Title | Location & Link | Type of Relationship |
| The Actin Binding Protein Fesselin is a Member of the Synaptopodin Family | http://hdl.handle.net/10342/3089 | The described resource references, cites, or otherwise points to the related resource. |