Cocaine Disrupts Pup-Induced Maternal Behavior in Juvenile and Adult Rats

ECU Author/Contributor (non-ECU co-authors, if there are any, appear on document)

Deborah L. Elliott (Creator)

Jay C. Elliott (Creator)

Amber Haslup (Creator)

Vivian E. Hofler (Creator)

Thomas M. Jarrett (Creator)

Josephine M. Johns (Creator)

Matthew S. McMurray (Creator)

Christopher L. Middleton (Creator)

Raessa Mirza (Creator)

Cheryl H. Walker (Creator)

Institution

East Carolina University (ECU )

Web Site: http://www.ecu.edu/lib/

Abstract: Impaired onset of maternal behavior in first generation rat dams was previously correlated with rearing by cocaine-treated dams and prenatal cocaine exposure. Pup-induced maternal behavior in non-lactating rats has not been examined with regard to cocaine exposure and rearing conditions. First generation male and female juveniles and young adult males reared by cocaine-treated or control dams and prenatally exposed to either cocaine or control conditions were tested for pup-induced maternal behavior at postnatal days 28 and 60. We now report disruptions in pup-induced maternal behavior in both 28 and 60 day old first generation offspring attributable to rearing condition and prenatal cocaine exposure. Originally published Neurotoxicology and Teratology Vol. 29 No. 6 Nov 2007

Additional Information

Publication

Other

Neurotoxicology and Teratology. 29:6(November-December 2007) p. 634-641.

Language: English

Date: 2011

Keywords

pup-induced maternal behavior, rats, cocaine, rearing environment, prenatal cocaine exposure

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