The effect of high-intensity exercise and carbohydrate supplementation on plasma visfatin
- UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
- Paul F. Mellick (Creator)
- Institution
- The University of North Carolina at Greensboro (UNCG )
- Web Site: http://library.uncg.edu/
- Advisor
- Laurie Wideman
Abstract: Plasma visfatin has been proposed to act as an insulin-mimetic hormone and to enhance glucose uptake. However, research regarding its insulin-like properties has been highly variable. Furthermore, its response to exercise, carbohydrate ingestion, and its overall relationship with blood glucose is not fully understood. PURPOSE: To examine the effect of high-intensity intermittent exercise and a carbohydrate supplementation (CHO) on plasma visfatin. METHODS: On 2 days separated by at least 3 days, 10 sprint-trained male subjects (age = 26.4 ± 5.3 yrs; Ht = 1.77 ± 0.03 m; Wt = 78.78 ± 9.10 kg; BF% = 13.96 ± 7.28%) completed 4 bouts of cycling (3 min each), at 50% of mean anaerobic power (based on a Wingate Test), with 6 min of rest between bouts. On the CHO day, subjects ingested 50g of CHO 30 min prior to exercise. On the control day, subjects ingested a sugar free artificially sweetened drink (CON) 30 min prior to exercise. Blood was drawn prior to supplement ingestion, 15 minutes before exercise, before and after each bout of exercise, and 15 and 30 minutes post exercise. Plasma visfatin, blood glucose, and plasma insulin were determined. Body composition and truncal fat were also assessed (DXA; Prodigy Advanced, GE Lunar). RESULTS: Visfatin was not significantly different between treatments (CHO vs CON) at any time point (p = 0.163), and was not significantly altered by exercise (p = 0.692). Insulin [25.65 vs 8.35 mU/l, CHO vs CON, respecitively] and glucose [138.57 vs 98.10 mg/dl, CHO vs CON, respectively] were both elevated after CHO ingestion and remained elevated throughout the first half of exercise. Baseline visfatin was significantly correlated with truncal fat (r2 = 0.6162, p < 0.05), but was not correlated with glucose or insulin. CONCLUSION: Although visfatin was correlated to truncal fat in healthy, sprint-trained males, it was not altered by high-intensity intermittent exercise or CHO supplementation.
The effect of high-intensity exercise and carbohydrate supplementation on plasma visfatin
PDF (Portable Document Format)
1556 KB
Created on 5/1/2013
Views: 2524
Additional Information
- Publication
- Dissertation
- Language: English
- Date: 2013
- Keywords
- Carbohydrate, Exercise, Glucose, Insulin, Visfatin
- Subjects
- Exercise $x Physiological aspects
- Carbohydrates $x Metabolism
- Carbohydrates in the body