Daniel A. Todd

  • Chemistry and Biochemistry, UNCG

There are 6 included publications by Daniel A. Todd :

TitleDateViewsBrief Description
Comparison of the chemistry and diversity of endophytes isolated from wild-harvested and greenhouse-cultivated yerba mansa (Anemopsis californica) 2015 481 With this study, we explored the identity and chemistry of fungal endophytes from the roots of yerba mansa [Anemopsis californica (Nutt.) Hook. & Arn. (Saururaceae)], a botanical traditionally used to treat infection. We compared the diversity of fun...
Ethanolic Echinacea purpurea Extracts Contain a Mixture of Cytokine-Suppressive and Cytokine-Inducing Compounds, Including Some That Originate from Endophytic Bacteria 2015 1410 Echinacea preparations, which are used for the prevention and treatment of upper respiratory infections, account for 10% of the dietary supplement market in the U.S., with sales totaling more than $100 million annually. In an attempt to shed light on...
Exploration of quorum sensing inhibition in gram positive bacterial pathogens using mass spectrometry 2015 1771 Antibiotics have been used as the primary treatment for bacterial infections since the 1940’s. Unfortunately, the use and misuse of antibiotics has led to the proliferation of antibiotic-resistant bacteria and resulted in the loss of antibiotic effic...
Reinforcement of Polymeric Nanoassemblies for Ultra-High Drug Loadings, Modulation of Stiffness and Release Kinetics, and Sustained Therapeutic Efficacy 2018 12 The optimization of current polymeric nanoparticle therapies is restricted by low drug loadings and limited tunability of core properties. To overcome these shortcomings, a novel self-association approach is utilized to fabricate a dual-loaded poly(1...
Secondary Metabolites from the Leaves of the Medicinal Plant Goldenseal (Hydrastis Canadensis) 2017 12 The study presented herein constitutes an extensive investigation of constituents in Hydrastis canadensis L. (Ranunculaceae) leaves. It describes the isolation and identification of two previously unknown compounds, 3,4-dimethoxy-2-(methoxycarbonyl)b...
Synthesis of Poly(1,2-Glycerol Carbonate)-Paclitaxel Conjugates and Their Utility as a Single High-Dose Replacement for Multi-Dose Treatment Regimens in Peritoneal Cancer 2017 54 Current chemotherapeutic dosing strategies are limited by the toxicity of anticancer agents and therefore rely on multiple low-dose administrations. As an alternative, we describe a novel sustained-release, biodegradable polymeric nanocarrier as a si...