Edward B. Tapscott

There are 4 included publications by Edward B. Tapscott :

TitleDateViewsBrief Description
Contractile activity restores insulin responsiveness in skeletal muscle of obese Zucker rats. 2011 38733 Both insulin and contraction stimulate glucose transport in skeletal muscle. Insulin-stimulated glucose transport is decreased in obese humans and rats. The aims of this study were (1) to determine if contraction-stimulated glucose transport was also...
An in vitro human muscle preparation suitable for metabolic studies. Decreased insulin stimulation of glucose transport in muscle from morbidly obese and diabetic subjects. 2011 38733 We have developed an in vitro muscle preparation suitable for metabolic studies with human muscle tissue and have investigated the effects of obesity and non-insulin-dependent diabetes mellitus (NIDDM) on glucose transport. Transport of 3-0- methylgl...
Insulin responsiveness in skeletal muscle is determined by glucose transporter (Glut4) protein level. 2011 38733 Glucose transport in skeletal muscle is mediated by two distinct transporter isoforms designated muscle/adipose glucose transporter (Glut4) and erythrocyte/HepG2/brain glucose transporter (Glutl) which differ in both abundance and membrane distributi...
Restoration of insulin responsiveness in skeletal muscle of morbidly obese patients after weight loss. Effect on muscle glucose transport and glucose transporter GLUT4. 2011 38733 A major defect contributing to impaired insulin action in human obesity is reduced glucose transport activity in skeletal muscle. This study was designed to determine whether the improvement in whole body glucose disposal associated with weight reduc...