R. Martin II Roop

There are 7 included publications by R. Martin II Roop :

TitleDateViewsBrief Description
Broad-Host-Range Expression Vectors with Tightly Regulated Promoters and Their Use To Examine the Influence of TraR and TraM Expression on Ti Plasmid Quorum Sensing 2011 64728 Experiments requiring strong repression and precise control of cloned genes can be difficult to conduct because of the relatively high basal level of expression of currently employed promoters. We report the construction of a family of vectors that c...
Deficiency of a Sinorhizobium meliloti bacA Mutant in Alfalfa Symbiosis Correlates with Alteration of the Cell Envelope 2011 64728 The BacA protein is essential for the long-term survival of Sinorhizobium meliloti and Brucella abortus within acidic compartments in plant and animal cells respectively. Since both the S. meliloti and B. abortus bacA mutants have an increased resist...
Genetic Organization and Iron-Responsive Regulation of the Brucella abortus 2 3-Dihydroxybenzoic Acid Biosynthesis Operon a Cluster of Genes Required for Wild-Type Virulence in Pregnant Cattle 2011 64728 Brucella abortus reportedly produces the monocatechol siderophore 2 3-dihydroxybenzoic acid (2 3-DHBA) in response to iron limitation. Nucleotide sequence analysis of the cloned DHBA biosynthesis locus from virulent B. abortus 2308 and genetic comple...
Opsonized Virulent Brucella abortus Replicates within Nonacidic Endoplasmic Reticulum-Negative LAMP-1-Positive Phagosomes in Human Monocytes 2011 64728 Cells in the Brucella spp. are intracellular pathogens that survive and replicate within host monocytes. Brucella maintains persistent infections in animals despite the production of high levels of anti-Brucellaspecific antibodies. To determine the e...
Production of the Siderophore 2 3-Dihydroxybenzoic Acid Is Required for Wild-Type Growth of Brucella abortus in the Presence of Erythritol under Low-Iron Conditions In Vitro 2011 64728 Production of the siderophore 2 3-dihyroxybenzoic acid (2 3-DHBA) is required for the wild-type virulence of Brucella abortus in cattle. A possible explanation for this requirement was uncovered when it was determined that a B. abortus dhbC mutant (B...
RecA and RadA Proteins of Brucella abortus Do Not Perform Overlapping Protective DNA Repair Functions following Oxidative Burst 2011 64728 Very little is known about the role of DNA repair networks in Brucella abortus and its role in pathogenesis. We investigated the roles of RecA protein DNA repair and SOS regulation in B. abortus. While recA mutants in most bacterial species are hyper...
Similarity to peroxisomal-membrane protein family reveals that Sinorhizobium and Brucella BacA affect lipid-A fatty acids 2011 64728 Sinorhizobium meliloti a legume symbiont and Brucella abortus a phylogenetically related mammalian pathogen both require the bacterial-encoded BacA protein to establish chronic intracellular infections in their respective hosts. We found that the bac...