Effect Of Apple Peel Extract Supplementation In Skeletal Muscle Of Aged Mice

ASU Author/Contributor (non-ASU co-authors, if there are any, appear on document)
Kierstin Davis (Creator)
Appalachian State University (ASU )
Web Site: https://library.appstate.edu/
Kevin Zwetsloot

Abstract: Apple peels contain naturally occurring bioactive compounds called triterpenoids that process properties that can enhance muscle mass and function. Triterpenoids exhibit a wide range of biological functions including antioxidant, anti-microbial, anti-inflammatory, and other anticancer activities. Triterpenoids also possess anabolic properties without androgenic side effects, therefore they might be a viable treatment for promoting muscle maintenance and growth. The expanded literature review, focused on the effects of apple peel extract on muscle health, replaced my research project. The molecular pathways were examined to understand how atrophy and hypertrophy occur in skeletal muscle. Several studies discussed the effects triterpenoids paired with resistance exercise, with a high fat diet, or alone can cause skeletal muscle to increase in mass, strength by increasing IGF-1, and the PKI3/Akt/mTORC signaling pathway.

Additional Information

Honors Project
Davis, K. (2020). Effect Of Apple Peel Extract Supplementation In Skeletal Muscle Of Aged Mice. Unpublished Honors Thesis. Appalachian State University, Boone, NC.
Language: English
Date: 2020
apple peel extract, skeletal muscle, sarcopenia, aging, sarcopenia interventions

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