GPCRs Moonlighting as Scramblases: Mechanism Revealed
- UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
- Patricia H. Reggio, Professor and Department Head (Creator)
- Institution
- The University of North Carolina at Greensboro (UNCG )
- Web Site: http://library.uncg.edu/
Abstract: Phospholipids can undergo transverse diffusion, changing leaflets in the bilayer via translocase or scramblase activity. In this issue of Structure, Morra et al. (2018) provide insight into the mechanism used by one scramblase, opsin, based on large-scale ensemble atomistic molecular dynamics simulations. Results support a proposed “credit card reader” model.
GPCRs Moonlighting as Scramblases: Mechanism Revealed
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Created on 3/30/2020
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Additional Information
- Publication
- Structure 26(2): 184-186
- Language: English
- Date: 2018
- Keywords
- scramblase, GPCR, phospholipid