|NspS, A PotD1 Homolog, Acts as a Spermidine Signal Sensor, Not a Transporter, in Vibrio Cholera
||Biofilm formation is important for the survival of Vibrio cholerae in its natural aquatic environments and within the human intestinal tract. We have previously shown that the absence of PotD1, the periplasmic binding protein for the spermidine ABC t...
|The Effect of Polyamines on Vibrio cholerae Virulence Properties
||Vibrio cholerae is the causative agent of the severe enteric disease, cholera. To be a virulent strain, the bacterium must be able to synthesize both cholera toxin and toxin-coregulated pilus (TCP). TCP has been shown to mediate microcolony formati...
|Characterization of Protein-Protein Interaction Within a Polyamine Responsive Signaling System in Vibrio Cholerae
||The Gram-negative bacterium Vibrio cholerae is a natural inhabitant of aquatic environments and the causative agent of the severe diarrheal disease cholera. This bacterium is able to form biofilms on both abiotic and biotic surfaces. Biofilm formatio...
|Characterization of the Norspermidine/Spermidine Transport Protein, PotD1, in Vibrio cholerae
||Biofilm formation increases antibiotic resistance among bacteria; therefore, a thorough understanding of the proteins and molecules affecting biofilm formation is necessary. PotD1, the substrate binding protein of the PotABCD1 spermidine transport sy...