| Title | Date | Views | Brief Description |
|---|
| A Pilot Study To Investigate The Effects Of Imperceptible Wrist Vibration On The Corticospinal Motor Excitability Of Healthy Adults |
2016 |
948 |
The study investigated changes in corticomotor excitability of healthy adults with imperceptible white-noise vibration applied to the wrist. Previous studies have shown that the application of unperceivable white-noise vibration to the wrist induced ... |
| RNA-Processing Genes Control Sensory Neuron Function In Drosophila Melanogaster |
2017 |
1260 |
The goal of this study was to identify genes involved in regulating the function of class IV multidendritic neurons (nociceptors) integral to the detection of thermal, mechanical, and photic stimuli. We used Drosophila melanogaster larvae as a model ... |
| A Genetic Screen For Wnt Signaling Factors That Regulate Drosophila Melanogaster Nociception |
2017 |
869 |
Nociception is the process by which sensory neurons in the periphery detect noxious stimuli and cause behavioral responses. The mechanisms behind the transduction of noxious sensory stimuli and the resulting behavior are still not fully known. In... |
| The Role Of RNA-Binding Protein Pumilio In Regulation Of Nociceptive Sensation |
2017 |
907 |
Nociception is the sensation of potentially tissue damaging stimuli, and is necessary for the survival of all animals. Without it, organisms would not be able to navigate their environment safely and efficiently, both avoiding potentially dangerous s... |
| Cellular Signaling Pathways Regulate Nociceptor Sensitivity To Noxious Stimuli In Drosophila Melanogaster Larvae |
2019 |
497 |
Chronic pain is a major public health concern that affects about 100 million Americans, generates $600 billion in healthcare costs, and is a major cause of missed work. For these reasons, it is important to research the cellular mechanisms of sensory... |
| The Role Of Translation Initiation Regulating Kinases, Lk6 And Tor, On Nociceptor Development And Function In Drosophila Melanogaster |
2019 |
827 |
Chronic pain affects over 100 million adults in the United States and costs the US over $500 billion dollars annually due to expenses associated with healthcare and lost productivity. Effective treatments for chronic pain are lacking due to our incom... |
| The Role Of Muscleblind In Nociception In Drosophila Melanogaster |
2022 |
202 |
Chronic pain affects more than 50 million U.S. adults and has an annual economic impact upwards of $650 billion. Chronic pain is commonly treated with opioids that momentarily reduce pain sensation but can be highly addicting and may not offer a long... |
| The Role Of Notch In Drosophila Nociceptor Function And Morphology |
2022 |
146 |
Chronic pain affects approximately 1 in 5 American adults, and costs around $600 billion annually. Available therapeutics do not sufficiently treat chronic pain, indicating that treatment methods must continue to expand. To develop new treatments, no... |
| The Roles Of Gaq And Phospholipase C Beta In Regulating Mechanosensory And Thermosensory Behavior In Drosophila |
2017 |
830 |
The ethics and appropriateness of speech-language pathology service provision to culturally and linguistically diverse (CLD) individuals in largely monolingual countries has been called into question in the past several years. This paper outlines met... |
| Nociceptor Sensitivity In Drosophila Melanogaster Larvae Is Controlled By RNA-Binding Proteins |
2018 |
469 |
Currently, there are significant gaps in understanding of the regulatory mechanisms involved in nociceptor sensitivity. Dysregulated nociceptor sensitivity is the likely pathogenesis in many types of chronic pain, a disease that ails over 100 million... |
| PVR, A Growth Factor Receptor, Plays A Role In Thermal Nociception |
2023 |
185 |
Across the globe, chronic pain affects approximately 1.5 billion people. In the United States, it costs approximately $600 billion dollars every year in lost labor, treatments, and healthcare. Therefore, it is important to identify and characterize t... |
| Roles Of eIF4A And eIF4G In Drosophila Nociception |
2019 |
792 |
Nociception refers to the detection of noxious mechanical, chemical, or thermal stimuli by specialized neurons called nociceptors. Sensitization of these nociceptor neurons in response to tissue damage or inflammation is a root cause of chronic pain.... |
| The Role Of RNA Binding Proteins And CRISPR/CAS9 As A Gene Editing Tool In Drosophila Nociception |
2023 |
354 |
Drosophila melanogaster is a powerful model organism to study nociception. The compact and easily manipulated genome provides an opportunity to determine the function of molecules involved in basal and sensitized nociception in both larval and adult ... |
| The Regulation Of parabss1 By spen And brm And Its Role In Seizure Susceptibility And Nociception Sensitivity In Drosophila |
2019 |
321 |
Seizures are defined by abnormal and synchronous firing of neurons within the central nervous system and epilepsy is persistent, spontaneous seizures. Single gene mutations have been linked to several epileptic disorders with most mutations occurring... |
| The Role Of eIF4E In Nociception Of Drosophila Melanogaster |
2021 |
294 |
Some cases of chronic pain arise from inappropriate sensitization as a result of changes in gene expression within the sensory neuron. Translational regulation is a known contributor to the required changes in gene expression. A known node for transl... |