Magnetoreception of photoactivated cryptochrome 1 in electrochemistry and electron transfer
- UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
- Taylor Levi Mabe (Creator)
- Jianjun Wei, Associate Professor (Creator)
- Institution
- The University of North Carolina at Greensboro (UNCG )
- Web Site: http://library.uncg.edu/
Abstract: Cryptochromes are flavoproteins whose photochemistry is important for crucial functions associated with phototropism and circadian clocks. In this report, we, for the first time, observed a magnetic response of the cryptochrome 1 (CRY1) immobilized at a gold electrode with illumination of blue light. These results present the magnetic field-enhanced photoinduced electron transfer of CRY1 to the electrode by voltammetry, exhibiting magnetic responsive rate constant and electrical current changes. A mechanism of the electron transfer, which involves photoinduced radicals in the CRY, is sensitive to the weak magnetic field; and the long-lived free radical FAD•– is responsible for the detected electrochemical Faradaic current. As a photoreceptor, the finding of a 5.7% rate constant change in electron transfer corresponding to a 50 µT magnetic field may be meaningful in regulation of magnetic field signaling and circadian clock function under an electromagnetic field. [The original abstract for this article contains (characters/images) that cannot be displayed here. Please click on the link below to read the full abstract and article.]
Magnetoreception of photoactivated cryptochrome 1 in electrochemistry and electron transfer
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Created on 6/23/2020
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Additional Information
- Publication
- ACS Omega, 2018, 3 (5), 4752-4759, DOI: 10.1021/acsomega.8b00645
- Language: English
- Date: 2018
- Keywords
- cryptochrome 1 (CRY1), magnetic response, tryptophan