A study of localized surface plasmon resonance nanoslit array and applications for chip-based protein detection
- UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
- Jianjun Wei, Associate Professor (Creator)
- Institution
- The University of North Carolina at Greensboro (UNCG )
- Web Site: http://library.uncg.edu/
Abstract: Ordered arrays of nanostructures in thin metal (Au) films have been studied for localized surface plasmon resonance (LSPR) sensing with a transmission spectral mode. We report on a nanoslit array device that is designed to permit extraordinary optical transmission (EOT) with a tunable primary peak in the visible to near infrared range and a spectral shape and light transmission that is determined by surface plasmon manipulation in the embedded gold film. Finite-difference time-domain (FDTD) simulation studies show that a nanoslit array device can provide a well-defined transmission resonance and display a monotonically increasing value of the resonance peak wavelength, ?max, with increasing period. Simulation studies show that the refractive index (RI) changes occurring on the in-slit gold surfaces contribute the most to the resonance transmission wavelength shift, suggesting that the strong confinement of LSPR in the narrow slit region is the origin of the sensitive RI response. These planar nanoslit array devices were used to detect the ligand binding protein, ß-lactoglobulin (ß-LG), with functionalization of specific binding retinals linked via a self-assembled monolayer at the array surfaces. These results illustrate the promise of nanoslit arrays for LSPR bio-detection in a lab-on-chip device platform.
A study of localized surface plasmon resonance nanoslit array and applications for chip-based protein detection
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Additional Information
- Publication
- JSM Nanotechnology & Nanomedicine., 2014, 2(2): 1024
- Language: English
- Date: 2014
- Keywords
- Localized surface plasmon resonance (LSPR), Nanoslit array, Optical transmission, Biosensor