Shaker short-tail, a spontaneous neurological mutant in the mouse

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Douglas Wahlsten, Visiting Professor (Creator)
The University of North Carolina at Greensboro (UNCG )
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Abstract: A spontaneous mutation that occurred in the Inbred strain BALB/cCF In 1980 proved to be inherited as a single autosomal recessive gene with complete penetrance. Homozygous recessive animals have a short or blunt tall, an irregular pattern of foliation of the cerebellum, delayed development of the righting reflex, and a wide variety of other peculiar behaviors. The effects of this mutation strongly resemble those of the shaker-short (st) gene reported by Dunn in 1934 that is now extinct. The gene designation, sst, is proposed for the new shaker short-tall mutation.

Additional Information

Journal of Heredity, 1983, 74(6), 421-425.
Language: English
Date: 1983
Mutation, Genetics, Mice, Nervous system

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