Mode of inheritance of deficient corpus callosum in mice

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Douglas Wahlsten, Visiting Professor (Creator)
The University of North Carolina at Greensboro (UNCG )
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Abstract: Many mice of the Inbred strain BALB/cCF have deficient corpus callosum, and a few of them have total absence of this large forebrain commissure. Reciprocal F1 hybrid crosses with the inbred strains A/J, C57BL/6J, and DBA/2J revealed that Inheritance of the defect Is completely recessive. Reciprocal backcrosses to BALB/cCF revealed that Inheritance is not attributable to a single Mendelian locus with the same degree of pens-trance as In the parent strain. The ac locus has not been rediscovered, Instead, there Is good reason to withdraw ac from current listings of Mendelian loci in the mouse.

Additional Information

Journal of Heredity, 1982, 73(4), 281-285.
Language: English
Date: 1982
Mendelian, Corpus callosum, Deficient, Brain structure, Genetics

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