Interpreting the Conductance Blockades of DNA Translocations Through Solid-State Nanopores

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Ethan W Taylor, Senior Research Professor (Creator)
The University of North Carolina at Greensboro (UNCG )
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Abstract: Solid-state nanopore electrical signatures can be convoluted and are thus challenging to interpret. In order to better understand the origin of these conductance changes, we investigate the translocation of DNA through small, thin pores over a range of voltage. We observe multiple, discrete populations of conductance blockades that vary with applied voltage. To describe our observations, we develop a simple model that is applicable to solid-state nanopores generally. These results represent an important step toward understanding the dynamics of the electrokinetic translocation process.

Additional Information

ACS Nano 2014, 8, 5, 4754–4760.
Language: English
Date: 2014
nanopore, DNA, translocation, conductance blockade, single molecule

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