Nanostructured metallic film plasmonics: fabrication and biosensing applications

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Taylor Levi Mabe (Creator)
The University of North Carolina at Greensboro (UNCG )
Web Site:
Jianjun Wei

Abstract: The research presented in this dissertation is interdisciplinary in nature. It covers the areas of micro- and nanofabrication, chemistry, materials science, and biological sensing. The running theme of the dissertation is the fabrication of micro- and nanostructures for use in plasmonic devices to aid in the optical detection of biomolecules. Phase I of the research focused on a bimetallic nanostructured (nanoslit) film to aid in improving the sensitivity in comparison to pure gold films. Phase II of the research investigated nanoledge structures (stair-step features) for their ability to trap biomolecules and aid in surface plasmon resonance sensing. Phase III of the research examined how to produce a fluidic dam, a microstructure with an overcut sidewall profile, which could aid in separating biological entities from the proteins of interest. Phase IV of the research assessed the use of the fluidic dam and nanoledge structures for detection of Troponin T, a biomarker used in the diagnosis of heart attacks. Phase V of the research focused on the design and microfabrication of a plasmonic device, which could study how surface plasmon resonance influences a photocurrent generated by immobilizing photosystem I in a nanoslit structure.

Additional Information

Language: English
Date: 2018
Microfabrication and Nanofabrication, Nanoledge and Nanoslit Structures, Nanostructured Metal Films, Plasmonic Biosensing, Point-of-care Diagnostics, Surface Plasmon Resonance
Materials science

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