Adamson, Amy

uncg

There are 9 item/s.

TitleDateViewsBrief Description
The Intracellular Consequences of the Interaction between Epstein-Barr Virus Protein BZLF1 and the Human Protein Pax5 2008 1656 Epstein-Barr virus (EBV) is a human herpes virus that is the cause of infectious mononucleosis and is associated with several types of cancers. These cancers include Burkitt's lymphoma, nasopharyngeal carcinoma, Hodgkin's disease, and a variety of le...
Inhibition of Influenza A Viral Replication by Activity Modulation of the M2 Viral Protein. 2010 3651 The Influenza A virus leads to yearly epidemics and occasional world-wide pandemics, as with the Spanish Influenza of 1918. The frequent mutation rate of the virus mandates that new vaccines be created often. Additionally, acquired resistance to anti...
Glycolytic control of vacuolar ATPase pump activity: a mechanism to regulate influenza viral infection 2012 2440 Influenza viruses are pathogens that can cause major pandemics in the human population, such as the Spanish Flu outbreak in 1918-1919, which caused about 50 million deaths worldwide. As the virus frequently mutates, vaccines and anti-viral drugs can ...
Interleukin-10 Promotes cell proliferation in Epstein-Barr infected B cells through activation of Ras/ERK and phosphorylation of c-Myc 2014 639 Epstein-Barr virus is a human herpes virus that in conjunction with Malaria is responsible for endemic Burkitt's lymphoma, a B-cell cancer. The main distinguishing characteristic of Burkitt's lymphoma is a constitutively active c-Myc protein. The tra...
Alterations in critical cellular pathways during lytic Epstein-Barr Virus infection 2018 40 Epstein-Barr Virus (EBV) is a human herpesvirus that infects approximately 90% of the global human population. Infection with EBV is associated with several diseases, such as Burkitt’s Lymphoma, nasopharyngeal carcinoma, and gastric carcinoma. In bot...
Yin-Yang 1 regulation of Epstein-Barr virus BRLF1 transcription is altered during mTORC1 inhibition in a cell type-specific manner 2018 42 Epstein-Barr virus (EBV) is a ubiquitous herpesvirus that infects individuals worldwide. EBV actively replicates and establishes a latent infection in epithelial cells and B cells, which can lead to diseases such as infectious mononucleosis and Burki...
Nanoparticle toxicity in Drosophila melanogaster: a case study with nickel, nickel oxide, and iron-nickel alloy nanoparticles 2018 100 With an increase use of nanomaterials, growing concerns have risen about their potential exposure to environment and the risk of side effects on human health. My research investigates the ecological and mechanistic insights of in vivo nanoparticle to...
The incidence of separation events of Saccharomyces cerevisiae in a flow displacement chamber: examining shear forces overcoming Flo11p mediated adhesion to an inert substrate 2018 162 Biofilms are present on surfaces that are exposed to a consistently aqueous environment and can be deleterious to human health. Fungal biofilm infections are a common problem in medical in-dwellings, specifically urinary catheters that need to remain...
Cell-specific regulation of immediate early gene BZLF1 in Epstein-Barr Virus under mTOR inhibition 2016 109 Epstein-Barr Virus (EBV) is a nearly ubiquitous human herpesvirus which infects epithelial cells and B-lymphocytes. Additionally, long-term EBV latency has been associated with various forms of cancers including Burkitt’s lymphoma, nasopharyngeal car...