Anti-Inflammatory Effects of an Herbal Medicine (Xuan-Ju Agent) on Carrageenan- and Adjuvant-Induced Paw Edema in Rats

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Wei Jia, Professor and Co-Director of the UNCG Center for Research Excellence in Bioactive Food Components (Creator)
The University of North Carolina at Greensboro (UNCG )
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Abstract: Xuan-Ju agent is an herbal formula containing aqueous extract of Formica fusca, Herba epimedii, Fructus cnidii, and Fructus lycii, all of which are reputed for their beneficial effects in the treatment of the immunodeficient diseases such as rheumatoid arthritis. We performed a study on the anti-inflammatory effects of this agent using carrageenan- and adjuvant-induced paw edema in rats. Xuan-Ju agent showed a marked inhibitory effect on edema in two models of inflammation in rats, at the dose of 0.20, 0.40 and 0.80 g/kg. Based on this study, Xuan-Ju agent is considered to be a potentially useful drug suitable for further evaluation for rheumatoid arthritis.

Additional Information

Journal of Ethnopharmacology, 89, 139-141
Language: English
Date: 2003
herbal extract, Xuan Ju, agents, anti-inflammatory effects, rheumatoid arthritis

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