A Study to Investigate the Role of Noncoding RNA miR146 Alpha as a Potential Biomarker in Prostate Cancer

ECSU Author/Contributor (non-ECSU co-authors, if there are any, appear on document)
Hirendra Banerjee, Professor (Creator)
Jeffrey Rousch, Professor (Contributor)
Elizabeth City State University (ECSU )
Web Site: https://www.ecsu.edu/academics/library/index.html

Abstract: There is a need for additional biomarkers for the diagnosis and prognosis of prostate cancer. MicroRNAs are a class of non-protein coding RNA molecules that are frequently dysregulated in different cancers, including prostate cancer and show promise as diagnostic biomarkers and targets for therapy. Here we describe the role of micro RNA 146 a (miR-146a) which may serve as a diagnostic marker for prostate cancer, as indicated from the data presented in this report. Also, a pilot study indicated differential expression of miR-146a in prostate cancer cell lines and tissues from different racial groups. This report provides a novel insight into understanding prostate carcinogenesis.

Additional Information

Language: English
Date: 2022
Prostate Cancer, Non Coding RNA, miR146 alpha, Biomarker

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