Economic and Health Burden of Rotavirus Gastroenteritis in Latin America

ASU Author/Contributor (non-ASU co-authors, if there are any, appear on document)
Richard Rheingans Ph.D., Department Chair (Creator)
Appalachian State University (ASU )
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Abstract: Objective. To estimate the health and economic burden of rotavirus gastroenteritis in hos-pital and outpatient settings in eight Latin American and Caribbean countries (Argentina, Brazil, Chile, Dominican Republic, Honduras, Mexico, Panama, and Venezuela). Methods. An economic model was constructed using epidemiological data from published articles, national health administration studies, and country-specific cost estimates. For each of the eight countries, the model estimated the rotavirus outcomes for the 2003 birth cohort during the first five years of life. The main outcome measures included health care costs, trans-portation costs, lost wages, and disease burden expressed in disability-adjusted life years. Es-timates were expressed in 2003 US dollars. All future costs and disability-adjusted life year estimates were discounted at a rate of 3%. Sensitivity analyses evaluated the impact of specific variables on the medical cost of treating rotavirus. Results. For every 1 000 children born during 2003 in the eight Latin American and Caribbean countries studied here, we estimated that rotavirus gastroenteritis would result in an average of 246 outpatient visits, 24 hospitalizations, 0.6 deaths, and US$ 7 971 in direct medical costs during their first five years of life. The incidence of rotavirus-associated outpa-tient visits and the cost of outpatient visits were predicted to have the largest impact on the total medical cost per child. Conclusions. Rotavirus gastroenteritis is likely to result in substantial disease and economic burden to health systems in Latin American and Caribbean countries, and the foreseeable bur-den should be an important consideration in evaluating the cost-effectiveness of vaccination.

Additional Information

Rheingans RD, Constenla D, Antil L, Innis BL and Breuer T (2007) "Economic and Health Burden of Rotavirus Gastroenteritis in Latin America" J Pan Am Health Org 21(4) pp. 192-204 Version of Record Available From
Language: English
Date: 2007
Rotavirus, gastroenteritis, costs and cost analysis, cost of illness, models, eco- nomic, Latin America, Caribbean Region

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