Ahmed, Maryam

asu

There are 9 item/s.

TitleDateViewsBrief Description
The Effects of Curcumin and Flavokavain B on the Oncolytic Activity of Vesicular Stomatitis Virus 2013 2232 A promising cancer treatment modality is the use of oncolytic viruses to kill cancer cells. One virus that is currently being studied as an oncolytic agent is vesicular stomatitis virus (VSV). We are interested in developing the rM51R-M virus, a matr...
The Effect Of Moringa Oleifera On The Oncolytic Activity Of Vesicular Stomatitis Virus In Cervical Cancer Cells 2015 2958 Traditional treatment methods for cervical cancer are often not cancer-specific and are associated with adverse side effects. Our lab focuses on developing vesicular stomatitis virus (VSV) as an oncolytic agent due to the natural ability of this viru...
Oncolytic Vesicular Stomatitis Virus Inhibits Cancer Cell Invasion Processes 2017 694 Vesicular stomatitis virus (VSV) is being investigated as an oncolytic agent due to its capacity to kill cancer cells while exhibiting low virulence in vivo. A trigger for cancer metastasis is the formation of structures known as invadopodia, which f...
Therapuetic Targeting Of Macrophage Populations By Oncolytic Vesicular Stomatitis Virus 2017 2822 The human immune system is dedicated to ridding the body of foreign pathogens. However, in the context of cancer members of the innate and adaptive immune systems, M2 macrophages in particular, contribute to tumor growth and metastasis and are thus a...
Vesicular Stomatitis Virus Suppresses The Phagocytic Capacity Of A Tumor-Promoting Macrophage Population 2021 85 Tumor-associated macrophages (TAMs) have been found in high numbers in aggressive breast cancers, where they often stimulate metastasis and suppress anti-tumor immunity. Such TAMs represent the alternatively activated M2 subtype, though they may exis...
The Type I Interferon Anti-Viral Pathway Contributes To Macrophage Polarization Following Infection With Oncolytic Vesicular Stomatitis Virus 2020 198 Vesicular stomatitis virus (VSV) is a promising oncolytic agent that directly kills cancer cells, but which also modulates immune elements within the tumor microenvironment. Here we were interested in how VSV affects tumor-associated macrophages (TAM...
Response Of M2 Macrophages In A Simulated Tumor Microenvironment To Infection With Vesicular Stomatitis Virus 2018 382 Vesicular Stomatitis Virus (VSV) is a good candidate for oncolytic therapy due to its ability to induce apoptosis in a number of different types of cells. VSV's effect on macrophages has not been studied in-depth. Here, the effects of infection with ...
Modulation Of Breast Tumor Associated Macrophages By Oncolytic Vesicular Stomatitis Virus 2019 422 High tumor-associated macrophage (TAM) densities in cancerous breast tissue often correlates with poor clinical outcomes. This can be attributed to the M2 macrophage subtype whose wound-healing and immunosuppressive functions promote cancer cell prol...
A Review Of Tumor-Associated Macrophage-Targeted Cancer Therapies 2021 104 Tumor-associated macrophages, or TAMs, make up a significant component of the tumor microenvironment and contribute to the human immune response to cancer. TAMs can either take a pro-tumorigenic form, promoted by pro-inflammatory cytokines, that faci...