Youker, Robert T.

WCU

There are 2 item/s.

TitleDateViewsBrief Description
Investigation of a multi-ligand approach to increase thermal stability of NBD1-?F508 domain of CFTR 2019 300 Cystic Fibrosis (CF) is the most common monogenic hereditary disease in Caucasians affecting greater than 70,000 persons worldwide. Primary symptoms of CF patients are electrolyte imbalance in epithelial cells creating thick mucus layers in the lung,...
Quantification of murine olfactory receptor 691 and 78 quaternary structure in hek293 cells using spatial intensity distribution analysis 2022 39 G-protein coupled receptors (GPCR) encompass a large number of protein receptors within the human genome. Because GPCRs are involved in numerous pathways including serotonin signaling in the brain, the receptors are often targets for drug development...