Browse All

Theses & Dissertations

Submissions

Quality of life and sleep quality of long-term survivors of cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Katharine E. Duckworth (Creator)
Institution
The University of North Carolina at Greensboro (UNCG )
Web Site: http://library.uncg.edu/
Advisor
Craig Cashwell

Abstract: Advancements in medical technology coupled with a more thorough comprehension of oncologic diseases has resulted in a burgeoning number of aggressive treatment options available to cancer patients and a gradual loosening of the association between cancer and timely death. With the advent of extended life expectancies, however, the need to investigate the human and overall life impact of cancer diseases and treatments has increased dramatically (Langenhoff et al., 2001). This need to examine considerations of quality of life becomes even more essential in the context of high-risk treatments, such as cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy (CS+HIPEC), an extensive procedure offered to select candidates with peritoneal carcinomatosis from a variety of primary origins (Levine et al., 2007). A biopsychosocial model of research and clinical care (e.g. Wilson & Cleary, 1995) underscores the many levels and interrelationships of clinical, demographic, and psychosocial variables impacting survivors of such an invasive medical procedure, yet a paucity of methodologically sound psychosocial studies with these long-term CS+HIPEC survivors exists. The purpose of this investigation was to enhance our understanding of the multidimensional quality of life (QOL) and sleep quality of survivors who have lived 12 or more months post-CS+HIPEC. Additionally, the contributions of surgical and biological variables to long-term QOL were examined, as were changes in QOL scores over time in a subset of the sample. This descriptive data acquired enriches our knowledge of CS+HIPEC survivors' quality of survivorship, informs prospective candidates' treatment decision making processes, and enhances the standard of care by serving as a foundation for future psychosocial interventions.

Additional Information

Publication
Dissertation
Language: English
Date: 2010
Keywords
Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy, Peritoneal carcinomatosis, Quality of life, Sleep quality
Subjects
Cancer $x Treatment $x Psychological aspects.
Cancer $x Treatment $x Physiological aspects.
Sleep $x Physiological aspects.
Psychophysiology.
Quality of life.