Exercise-induced growth hormone during acute sleep deprivation

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Laurie Wideman, Associate Professor (Creator)
Institution
The University of North Carolina at Greensboro (UNCG )
Web Site: http://library.uncg.edu/

Abstract: The effect of acute (24-h) sleep deprivation on exercise-induced growth hormone (GH) andinsulin-like growth factor-1 (IGF-1) was examined. Ten men (20.6 ± 1.4 years) completed tworandomized 24-h sessions including a brief, high-intensity exercise bout following either a nightof sleep (SLEEP) or (24-h) sleep deprivation (SLD). Anaerobic performance (mean power [MP],peak power [PP], minimum power [MinP], time to peak power [TTPP], fatigue index, [FI]) andtotal work per sprint [TWPS]) was determined from four maximal 30-sec Wingate sprints on acycle ergometer. Self-reported sleep 7 days prior to each session was similar between SLEEPand SLD sessions (7.92 ± 0.33 vs. 7.98 ± 0.39 h, P = 0.656, respectively) and during the actualSLEEP session in the lab, the total amount of sleep was similar to the 7 days leading up to thelab session (7.72 ± 0.14 h vs. 7.92 ± 0.33 h, respectively) (P = 0.166). No differences existed inMP, PP, MinP, TTPP, FI, TWPS, resting GH concentrations, time to reach exercise-inducedpeak GH concentration (TTP), or free IGF-1 between sessions. GH area under the curve (AUC)(825.0 ± 199.8 vs. 2212.9 ± 441.9 µg/L*min, P < 0.01), exercise-induced peak GH concentration(17.8 ± 3.7 vs. 39.6 ± 7.1 µg/L, P < 0.01) and ?GH (peak GH – resting GH) (17.2 ± 3.7 vs. 38.2± 7.3 µg/L, P < 0.01) were significantly lower during the SLEEP versus SLD session. Our resultsindicate that the exercise-induced GH response was significantly augmented in sleep-deprivedindividuals.

Additional Information

Publication
Physiological Reports
Language: English
Date: 2014
Keywords
anaerobic, GH, High-intensity exercise, sleep loss, sprint exercise

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