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Oberlies, Nicholas

UNCG

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TitleDateViewsBrief Description
Use of adsorbent resins in fermentations of bacteria obtained from the red soils of the Kingdom of Jordan and the isolation and structure elucidation of cytotoxic xanthones from an unidentified fungus 2012 246 Part I: Adsorbent resins are used in industrial fermentations to help boost the production of antibiotics. The resins used here were utilized to help speed the drug discovery process by eliminating the time-consuming step of freeze-drying the ferment...
Fingolimod (Gilenya; FTY720): a recently approved multiple sclerosis drug based on a fungal secondary metabolite and the creation of a natural products pure compound database and organized storage system 2012 5244 Fingolimod (Gilenya; FTY720), a synthetic compound based on the fungal secondary metabolite, myriocin (ISP-I), is a potent immunosuppressant that was approved in September 2010 by the U.S. FDA as a new treatment for multiple sclerosis (MS). Fingolimo...