McIntosh, Michael

UNCG

There are 6 item/s.

TitleDateViewsBrief Description
Impact of trans-10, cis-12 conjugated linoleic acid on interleukin (IL)-6 and IL-8 and adipogenic genes in cultures of human adipose tissue explants 2005 1050 "Obesity has reached epidemic proportions in the United States, currently ranking second among causes of preventable deaths. Our research group has shown in cultures of differentiated human adipocytes that 30 uM trans-10, cis-12 Conjugated Linoleic ...
The antiobesity mechanism of conjugated linoleic acid 2009 2356 Given the steady rise in obesity worldwide, it is important to identify dietary compounds that prevent adiposity. One dietary strategy is supplementation with conjugated linoleic acid (CLA), which has been demonstrated to reduce body fat mass. Howeve...
Grape powder extract (GPE) attenuates markers of inflammation in human macrophages. 2010 1218 Obesity is linked to chronic inflammation in white adipose tissue (WAT) which is exacerbated by infiltrating macrophages (MΦ)s. Grape powder extract (GPE) contains polyphenols that have the potential to prevent this inflammatory response that c...
Conjugated linoleic acid (CLA) promotes inflammation to a greater extent in human adipocytes compared to preadipocytes 2011 4267 Due to the increasing prevalence of obesity and diabetes among children and adults worldwide, it is imperative to identify dietary strategies that promote weight control. One potential anti-obesity compound is conjugated linoleic acid (CLA), sold wor...
Grape polyphenols attenuate inflammation and insulin resistance in human adipocytes and obese mice 2012 6456 Obesity is rapidly increasing worldwide among all age groups. Insulin resistance or type 2 diabetes is one of several debilitating health problems associated with obesity. An emerging feature of obesity and type 2 diabetes is their linkage with chron...
Anti-obesity mechanisms of conjugated linoleic acid (CLA): role of inflammatory signaling and browning in white adipose tissue 2015 262 Overweight and obesity are the most widespread nutritional diseases in the U.S., which greatly increase chronic disease risks and mortality. Therefore, it is urgent to develop a relatively efficacious and safe strategy for the weight management. Cons...