Jia, Zhenquan

UNCG

There are 5 item/s.

TitleDateViewsBrief Description
Enhancement of endogenous glutathione and NQO1 by triterpenoid CDDO-Im in SH-SY5Y cells: protection against neurotoxicant-mediated cytotoxicity 2013 346 Evidence suggests oxidative and electrophilic stress as a major factor contributing to the neuronal cell death in neurodegenerative disorders, especially Parkinson's disease (PD). Early depletion in the levels of thiol antioxidant glutathione (GSH), ...
Protection of HepG2 cells from acrolein toxicity by CDDO-Im via glutathione-mediated mechanism 2013 1664 Acrolein is an environmental toxicant, mainly found in smoke released from incomplete combustion of organic matter. The compound is ubiquitously found in endogenous as well as exogenous environment. Several studies showed that exposure to acrolein ca...
Studies of environmental pollutant acrolein-induced endothelial dysfunction: the role of glutathione and nf-kappab 2015 235 Environmental pollutant exposure has gained considerable attention as a potential risk factor contributing towards cardiovascular diseases (CVDs). Acrolein is a highly reactive electrophilic aldehyde known for its ubiquitous presence in the atmospher...
Doxorubicin-induced cytotoxicity in rat myocardial H9c2 cells: the roles of reactive oxygen species and redox balance 2017 331 Doxorubicin (Dox) is one of the most potent anti-neoplastic agents approved by the Food and Drug Administration. Its efficacy, however, is limited due to its well-documented cardiotoxic side effect. Since the first observation of this dosage-dependen...
Carbon nanodots in endothelial cells and C57BL/6 mice: a study of toxicity and anti-inflammatory effect 2018 66 The advancement of therapy for cardiovascular disease (CVD) is paramount to public health, as it is the leading global cause of mortality [1]. Nanomedicine provides new opportunities in the ongoing efforts to reduce the economic and healthcare conseq...