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Theses & Dissertations


Raner, Gregory M.


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TitleDateViewsBrief Description
Isotopic labeling of heme in dehaloperoxidase and CYP102A2 for NMR studies 2007 1223 "13C NMR has been shown to be a powerful tool for probing the electronic distribution in paramagnetic hemes and hemoproteins. Methods that can measure the coordination state and electronic structure of the paramagnetic hemes and hemoproteinscan be v...
Regulation of cytochrome P450 2A6 and phase II enzymes by unsaturated aldehydes 2009 479 Human Phase I and Phase II drug metabolizing enzymes are known to interact with foreign chemicals that enter the body as a defense mechanism, however, it is often the case that unwanted interactions can occur. Phase I metabolism may form reactive ...