Livesay, Dennis R.

UNCC

There are 2 item/s.

TitleDateViewsBrief Description
A virtual pebble game to ensemble average graph rigidity 2011 520 Previous works have demonstrated that protein rigidity is related to thermodynamic stability, especially under conditions that favor formation of native structure. Mechanical network rigidity properties of a single conformation are efficiently calcul...
Elucidating the effects of mutation and evolutionary divergence upon protein structure quantitative stability/flexibility relationships 2012 309 The importance of flexibility and stability on protein function has been recognized for over five decades. A protein must be flexible enough to mediate a reaction pathway, yet rigid enough to achieve high fidelity in molecular recognition. To underst...