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A method for the determination of the ingredients of several dietary supplements by liquid chromatography

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Whitney Leigh Taylor (Creator)
Institution
The University of North Carolina at Greensboro (UNCG )
Web Site: http://library.uncg.edu/
Advisor
Brent Dawson

Abstract: The category of products known as dietary supplements covers a wide range of products including multivitamins, herbal supplements and energy drinks. High performance liquid chromatography (HPLC) is a common analytical technique for pharmaceuticals. This study presents an HPLC method for the quantitation of several ingredients in dietary supplements Lentra, Prolent, and Somni-TR. Photodetection by polydiacetylene is another quantitative method. Polydiacetylenes have two optical states, a "red" and a "blue" state, and an irreversible transition can be triggered from the blue to the red state by the binding of an analyte to the polymer. The potential usefulness of PDA lies in its ability to act as both receptor and transducer. In this study, attempts were made to synthesize several diacetylene monomers which could be used in PDA thin films or vesicles. These attempts included several different chain lengths and functional groups.

Additional Information

Publication
Thesis
Language: English
Date: 2011
Keywords
Diacetylenes, Dietary supplements, HPLC
Subjects
Dietary supplements $x Analysis
High performance liquid chromatography $x Industrial applications