AROMATASE PROTEIN CONTENT IN GLUTEAL AND ABDOMINAL SUBCUTANEOUS ADIPOSE TISSUE IN PREMENOPAUSAL CAUCASIAN AND AFRICAN AMERICAN WOMEN

ECU Author/Contributor (non-ECU co-authors, if there are any, appear on document)
Elizabeth Cooper (Creator)
Institution
East Carolina University (ECU )
Web Site: http://www.ecu.edu/lib/

Abstract: OBJECTIVE: To determine if aromatase protein content differs in abdominal and gluteal adipose tissue and to determine if there are racial differences in aromatase protein content that might influence racial differences in regional body fat distribution in overweight to obese premenopausal women. MATERIALS/METHODS: Biopsies of the subcutaneous abdominal and gluteal adipose tissue were performed in 15 premenopausal women (7 C/8 AA , 25.1 + 1.8 years , BMI 29.5 + 0.5kg/m(2)). Adipose tissue protein content was measure by western blot analysis. Independent sample t-tests were used to determine racial differences in subject characteristics and sex hormones. Two-way repeated measure ANOVA (race x region) was used to determine racial differences (C versus AA) in estrogen receptor expression in the abdominal and gluteal SAT. RESULTS: Aromatase protein content was not different between races or regions: C abdominal 0.25±0.06 , C gluteal 0.25±0.12 , AA abdominal 0.35±0.08 , AA gluteal 0.32±0.09 arbitrary units (2-way ANOVA; race x region p=0.73 , race p=0.46 , region p=0.71). CONCLUSIONS: This study showed no significant differences in aromatase protein content between regions or races in the observed group. No regional or racial differences in aromatase protein content were detected in this study.

Additional Information

Publication
Thesis
Language: English
Date: 2017
Keywords
aromatase, adipose, race, estrodiol, lipolysis
Subjects

Email this document to

This item references:

TitleLocation & LinkType of Relationship
AROMATASE PROTEIN CONTENT IN GLUTEAL AND ABDOMINAL SUBCUTANEOUS ADIPOSE TISSUE IN PREMENOPAUSAL CAUCASIAN AND AFRICAN AMERICAN WOMENhttp://hdl.handle.net/10342/6137The described resource references, cites, or otherwise points to the related resource.