Surface plasmon resonance: a label-free tool for cellular analysis

UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
Christopher Kepley, Associate Professor (Creator)
The University of North Carolina at Greensboro (UNCG )
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Abstract: Surface plasmon resonance (SPR) is a popular technique that allows for sensitive, specific, label-free and real-time assessment of biomolecular interactions. SPR is a nondestructive, modular and flexible tool for various applications in biomedical sciences ranging from cell sorting, cell surface characterization and drug discovery. In this review, we will discuss more specifically how SPR is used to monitor the dynamics of various types of cellular binding events and morphological adherence changes in response to external stimuli.

Additional Information

Nanomedicine, 2015;10(11):1833-46.
Language: English
Date: 2015
bacterial adherence properties, biomolecular interactions, cell sorting, cellular detection, cellular morphology alterations, cellular secretions, long-range surface plasmon resonance, nanoscale cellular dynamics, optical biosensor, single-cell analysis

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