Diffusion and perfusion weighted magnetic resonance imaging for tumor volume definition in radiotherapy of brain tumors

ECU Author/Contributor (non-ECU co-authors, if there are any, appear on document)

Xu Bai (Creator)

Yuanming Feng (Creator)

Yu Guo (Creator)

Lu Guo (Creator)

Gang Wang (Creator)

Zhaoxiang Ye (Creator)

Tonggang Yu (Creator)

Institution

East Carolina University (ECU )

Web Site: http://www.ecu.edu/lib/

Abstract: "Abstract Accurate target volume delineation is crucial for the radiotherapy of tumors. Diffusion and perfusion magnetic resonance imaging (MRI) can provide functional information about brain tumors, and they are able to detect tumor volume and physiological changes beyond the lesions shown on conventional MRI. This review examines recent studies that utilized diffusion and perfusion MRI for tumor volume definition in radiotherapy of brain tumors, and it presents the opportunities and challenges in the integration of multimodal functional MRI into clinical practice. The results indicate that specialized and robust post-processing algorithms and tools are needed for the precise alignment of targets on the images, and comprehensive validations with more clinical data are important for the improvement of the correlation between histopathologic results and MRI parameter images."

Additional Information

Publication

Other

Radiation Oncology. 2016 Sep 21;11(1):123

Language: English

Date: 2016

Keywords

Tumor volume definition, Perfusion, Diffusion, Radiotherapy, Brain tumors

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