Real-time compression feedback for patients with in-hospital cardiac arrest: a multi-center randomized controlled clinical trial

ECU Author/Contributor (non-ECU co-authors, if there are any, appear on document)

Reza,Vahedian-Azimi,Amir,Farzanegan,Behrooz,Bashar R.,Hajiesmaeili,Mohammadreza,Shojae,Seyedpouzhia,M Goharani (Creator)

Institution

East Carolina University (ECU )

Web Site: http://www.ecu.edu/lib/

Abstract: Objective: To determine if real-time compression feedback using a non-automated hand-held device improvespatient outcomes from in-hospital cardiac arrest (IHCA).Methods: We conducted a prospective, randomized, controlled, parallel study (no crossover) of patients with IHCA inthe mixed medical--surgical intensive care units (ICUs) of eight academic hospitals. Patients received either standardmanual chest compressions or compressions performed with real-time feedback using the Cardio First Angelâ„¢ (CFA)device. The primary outcome was sustained return of spontaneous circulation (ROSC), and secondary outcomes weresurvival to ICU and hospital discharge.Results: One thousand four hundred fifty-four subjects were randomized; 900 were included. Sustained ROSC wassignificantly improved in the CFA group (66.7% vs. 42.4%, P < 0.001), as was survival to ICU discharge (59.8% vs. 33.6%)and survival to hospital discharge (54% vs. 28.4%, P < 0.001). Outcomes were not affected by intra-group comparisonsbased on intubation status. ROSC, survival to ICU, and hospital discharge were noted to be improved in inter-groupcomparisons of non-intubated patients, but not intubated ones.Conclusion: Use of the CFA compression feedback device improved event survival and survival to ICU and hospitaldischarge.

Additional Information

Publication

Other

Language: English

Date: 2019

Keywords

CPR, Resuscitation, Chest compression, Cardio First Angelâ„¢, Critical care, Intensive care

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