Apparatus and method for measuring physiological characteristics of an intact trachea in vitro

ECU Author/Contributor (non-ECU co-authors, if there are any, appear on document)
Jeffrey Fedan (Creator)
Michael Van Scott (Creator)
Institution
East Carolina University (ECU )
Web Site: http://www.ecu.edu/lib/

Abstract: Apparatus and methods for measuring smooth muscles responses (relaxation and contraction) , transepithelial potential difference , and/or transepithelial impedance of an intact trachea in vitro. In particular embodiments , the apparatus includes a perfusion device on which an extracted , intact trachea is mounted. The perfusion device and the trachea are immersed in an extraluminal bath , which is isolated from the perfusion liquid flowing through the trachea. A set of voltage-sensing electrodes is provided for measuring the transepithelial potential difference across the trachea wall. A set of current electrodes is provided for inducing an electrical current to flow across the trachea wall in order to determine transepithelial impedance.

Additional Information

Publication
Other
Language: English
Date: 2011
Keywords
Muscle response, endotracheal, oesophageal, gastric, probe
Subjects

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TitleLocation & LinkType of Relationship
Apparatus and method for measuring physiological characteristics of an intact trachea in vitrohttp://hdl.handle.net/10342/7564The described resource references, cites, or otherwise points to the related resource.