Dohm, G. Lynis


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Modulation of IKKβ with AMPK Improves Insulin Sensitivity in Skeletal Muscle 2011 193814 Activation of the insulin receptor substrate (IRS)-1 is necessary for proper transduction of the insulin signal. IRS-1 serine312(human)/307(rodent) phosphorylation however results in disruption of this signal and subsequent insulin resistance. Inflam...