Electrochemical Study of DPPH Radical Scavenging for Evaluating the Antioxidant Capacity of Carbon Nanodots
- UNCG Author/Contributor (non-UNCG co-authors, if there are any, appear on document)
- Jianjun Wei, Associate Professor (Creator)
- Institution
- The University of North Carolina at Greensboro (UNCG )
- Web Site: http://library.uncg.edu/
Abstract: Carbon nanodots (CNDs) have become one of the potential candidates for antioxidants due to their excellent luminescence, biocompatibility, and lower cytotoxicity. While CNDs have experienced some research on radical scavenging activity via UV–vis spectroscopy, the relationship between reserved 2,2-diphenyl-1-picrylhydrazyl radical (DPPH•) concentration and CNDs’ incubation concentration remains unclear. This work describes an electrochemical study on the changes of redox peaks of the oxidation of DPPH• at gold electrodes with addition of different concentrations of a type of microwave-synthesized CND (U-dots). The result is consistent with a UV–vis absorption dose-dependent study used to quantify the antioxidation activities. Combined with standard heterogeneous electron-transfer rate constant analysis, electrochemical study gives a coupled hydrogen atom transfer (HAT) mechanism for DPPH• scavenging by the U-dots. This work provides a new perspective on the antioxidative study of the U-dots, which may aid their development for practical use in biomedicine. [The original abstract for this article contains (characters/images) that cannot be displayed here. Please click on the link below to read the full abstract and article.]
Electrochemical Study of DPPH Radical Scavenging for Evaluating the Antioxidant Capacity of Carbon Nanodots
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Created on 6/10/2020
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Additional Information
- Publication
- Journal of Physical Chemistry C. 2017, 121 (34), 18635–18642
- Language: English
- Date: 2017
- Keywords
- carbon nanodots (CNDs), DPPH radical, electrochemistry, U-dots, antioxidation activity