Ece Karatan Ph.D.

There are 11 included publications by Ece Karatan Ph.D.:

TitleDateViewsBrief Description
Effects Of Polyamines On Vibrio Cholerae Virulence Properties 2013 1296 Vibrio cholerae is the causative agent of the severe enteric disease cholera. To cause cholera the bacterium must be able to synthesize both cholera toxin (CT) and toxin-coregulated pilus (TCP) which mediates auto-agglutination and is required for co...
Elevated Levels Of The Norspermidine Synthesis Enzyme Nspc Enhance Vibrio Cholerae Biofilm Formation Without Affecting Intracellular Norspermidine Concentrations 2012 1073 Biofilm formation in Vibrio cholerae is in part regulated by norspermidine, apolyamine synthesized by the enzyme carboxynorspermidine decarboxylase(NspC). The absence of norspermidine in the cell leads to a marked reductionin V. cholerae biofilm form...
Increased Abundance Of Gallionella Spp., Leptothrix Spp. And Total Bacteria In Response To Enhanced Mn And Fe Concentrations In A Disturbed Southern Appalachian High Elevation Wetland 2012 1393 The Sorrento wetland hosts several Fe- and Mn-rich seeps that are reported to have appeared after the area was disturbed by recent attempts at development. Culture-independent and culture-based analyses were utilized to characterize the microbial com...
Molecular Recognition Properties Of FN3 Monobodies That Bind The Src SH3 Domain 2004 1152 We have constructed a phage-displayed library based on the human fibronectin tenth type III domain (FN3) scaffold by randomizing residues in its FG and BC loops. Screening against the SH3 domain of human c-Src yielded six different clones. Five of th...
Nsps, A Predicted Polyamine Sensor, Mediates Activation Of Vibrio Cholerae Biofilm Formation By Norspermidine 2005 1254 Vibrio cholerae is both an environmental bacterium and a human intestinal pathogen. The attachment of bacteria to surfaces in biofilms is thought to be an important feature of the survival of this bacterium both in the environment and within the huma...
Relative Contributions Of Norspermidine Synthesis And Signaling Pathways To The Regulation Of Vibrio cholerae Biofilm Formation 2017 749 The polyamine norspermidine is one of the major polyamines synthesized by Vibrionales and has also been found in various aquatic organisms. Norspermidine is among the environmental signals that positively regulate Vibrio cholerae biofilm formation. T...
Role For Glycine Betaine Transport In Vibrio Cholerae Osmoadaptation And Biofilm Formation Within Microbial Communities 2005 566 Vibrio cholerae is a halophilic facultative human pathogen found in marine and estuarine environments. Accumulation of compatible solutes is important for growth of V. cholerae at NaCl concentrations greater than 250 mM. We have identified and charac...
Signals, Regulatory Networks, And Materials That Build And Break Bacterial Biofilms 2009 1484 No Abstract Available
Spermidine Regulates Vibrio Cholerae Biofilm Formation Via Transport And Signaling Pathways 2009 1393 Vibrio cholerae, the causative agent of the devastating diarrheal disease cholera, canform biofilms on diverse biotic and abiotic surfaces. Biofilm formation isimportant for the survival of this organism both in its natural environment andin the huma...
Spermine Inhibits Vibrio cholerae Biofilm Formation Through The NspS-MbaA Polyamine Signaling System 2017 752 The aquatic bacterium and human intestinal pathogen, Vibrio cholerae, senses and responds to a variety of environment-specific cues to regulate biofilm formation. Specifically, the polyamines norspermidine and spermidine enhance and repress V. choler...
Vibrio Cholerae Nsps, A Homologue Of ABC-Type Periplasmic Solute Binding Proteins, Facilitates Transduction Of Polyamine Signals Independent Of Their Transport 2014 1557 The polyamines norspermidine and spermidine are among the environmental signals that regulate Vibrio cholerae biofilm formation. The effects of these polyamines are mediated by NspS, a member of the bacterial periplasmic solute binding protein superf...