Seals, Darren

ASU

There are 3 item/s.

TitleDateViewsBrief Description
Examining the Effect of Tks5 Sh3 Domain Mutations on Invadopodia Localization and Development in Cancer Cells 2015 743 Metastasis, the process by which cancers spread from their site of origin to distant anatomic sites, accounts for about ninety percent of all cancer deaths. Metastasis occurs when cancer cells acquire the invasive behaviors necessary for breaching ti...
The Role Of TKS5 SH3 Domains In Invadopodia Development And Activity 2016 715 One mechanism by which cancer cells metastasize is through the formation of actin-rich structures called invadopodia. Tks5 is a Src tyrosine kinase substrate and scaffolding protein necessary for invadopodia formation and associated extracellular ma...
The Cytotoxic Effects Of Vesicular Stomatitis Virus On THP-1 Macrophages 2018 16 Cancer cells do not act autonomously. The interaction between cancer cells and other ‘normal’ cell types creates a tumor microenvironment conducive for the growth and progression of the disease. Tumor-associated macrophages (TAMs) are among the immun...